PTEN and familial papillary or follicular thyroid carcinoma: The characteristics of S-FNMTC are better defined, which means that sometimes, from the histopathological and/or immunohistochemical features of the thyroid tumors, the existence of a PTEN-hamartoma tumor syndrome or a familial adenomatous polyposis can be suggested; this condition, however, must be genetically confirmed from the patient’s blood samples (4, 5).