On the one hand, experiments in vitro and in vivo were lacking, and further QPCR and Western blot were needed to verify the expression of CCL22 as well as of other differentially expressed genes (BIRC3, CPT1B, ELMO1, PLA2G4C, and SLC25A2) in CRC cell lines infected by F. nucleatum. The gene discussed is PLA2G4C; the disease is colorectal carcinoma.