Treatment with the water-soluble polysaccharide (PTP) (10, 20, and 40 mg/kg) prepared from the roots of Polygala tenuifolia could exert potential anti-angiogenesis effects by significantly downregulating the protein and mRNA levels of EGFR, VEGF, and CD34 (Hematopoietic progenitor cell antigen) in the tumor-bearing BALB/c mice, resulting in the suppression of tumor growth (62). Here, VEGFA is linked to neoplasm.