EPHA1 and cataract: From studies using mice to understand the roles of Eph-ephrin signaling in cataractogenesis, the strain background can greatly influence the phenotype and severity and progression of cataracts (Cheng and Gong, 2011; Shi et al., 2012; Cheng et al., 2013; Son et al., 2013; Biswas et al., 2016; Zhou and Shiels, 2018).