EPHA2 and Age-related cataract: Several nsSNPs in EPHA2 affect the stability and translational regulation of the protein (Lin et al., 2014; Li et al., 2016; Li et al., 2021) and have been associated with congenital and age-related cataracts in humans (Jun et al., 2009; Kaul et al., 2010; Dave et al., 2013; Zhai et al., 2019; Li et al., 2021).