TGFB1 and allergic disease: In general, probiotics are associated with a decrease in inflammation by increasing butyrate production and induction of tolerance with an increase in the ratio of cytokines such as IL-10/IFN-γ, Treg/TGF-β, reducing serum eosinophil levels, and the expression of metalloproteinase-9 which contribute to the improvement of the allergic disease's symptoms [17, 18].