F11R and familial pancreatic carcinoma: As shown in Figures 4(a) and 4(b), the F11R knockdown cells significantly blocked pancreatic cancer cell cycle at G0/G1 phase (control group 36.29 ± 4.11%, vector group 31.98 ± 0.16%, and F11R-KD group 50.56 ± 2.96%), with statistically significant differences (P < 0.05).