VHPKQHR (VHP) is a peptide targeted to VCAM-1 identified by phage display technology and has been applied to target atherosclerotic plaque (Nahrendorf et al., 2006; Xu et al., 2019), but the use of VHP combined with USPIO for RA targeted imaging has not been reported yet. The gene discussed is VCAM1; the disease is rheumatoid arthritis.