By the clinical point of view, ETV6-NTRK3 fused sarcomas were reported as aggressive tumours, regardless of the grade of cytological atypia (18,25); we described two neoplasms with ETV6-NTRK3 fusion showing an indolent course, chemosensitive and without any signs of recurrence or metastatic spread, in contrast with what previously reported, so that the fusion partner does not seem a potential marker to predict prognosis. The gene discussed is ETV6; the disease is neoplasm.