We explored results returned by searching PubMed and Google Scholar using the terms “chemokines AND trigeminal pain,” “chemokines AND migraine,” and “chemokines AND trigeminal neuralgia,” as well as permutations of “each chemokine” (e.g., CCL2, CX3CL1, etc.), AND the terms “Trigeminal Pain” or “TMJ” or “Tooth Pain” or “Dental pain” or “Trigeminal Ganglion” or “Trigeminal Pain.” This evidence concerns the gene CCL2 and trigeminal nerve disorder.