DUSP2 and Familial prostate cancer: DUSP2 is expressed at low levels in a variety of tumors, such as prostate cancer, pancreatic cancer, colon cancer, and leukemia, and it participates in the regulation of tumor development through various signaling pathways (Rohan et al., 1993; Hartmann et al., 2016; Hou et al., 2017; Hu R. et al., 2018; Yin et al., 2019).