SKA3 is highly expressed in malignant tumors such as colon cancer, liver cancer, cervical cancer, and prostate cancer and plays an important role in cancer occurrence and development (Lee et al., 2015; Chuang et al., 2016; Hu R. et al., 2018; Hou et al., 2019). This evidence concerns the gene SKA3 and malignant colon neoplasm.