SKA3 is highly expressed in malignant tumors such as colon cancer, liver cancer, cervical cancer, and prostate cancer and plays an important role in cancer occurrence and development (Lee et al., 2015; Chuang et al., 2016; Hu R. et al., 2018; Hou et al., 2019). The gene discussed is SKA3; the disease is Familial prostate cancer.