KEGG analysis revealed that the six hub targets were mainly associated with immune system (C-type lectin receptor (CLR) signaling pathway, Toll-like receptor (TLR) signaling pathway, IL-17 signaling pathway and Fc epsilon RI signaling pathway), signal transduction (TNF signaling pathway and VEGF signaling pathway) and infectious disease (Figure 3D). This evidence concerns the gene IL17A and infectious disease.