DNAH8 and Alzheimer disease: The biological process of Gene Ontology (GO) analysis revealed that these differentially expressed proteins were primarily enriched in the positive regulation of autophagosome, presynaptic active zone membrane, ATPase activator activity, postsynaptic potential, postsynapse assembly, which is consistent with the fact that the pathology of AD correlates positively with synaptic function in hippocampal neurons (Figure 6A).