No changes were detected in the plasma sE-sel (Figure 4F), sICAM-1 (Figure 4G), vWF (Figure 4H), and PAI-1 (Figure 4I), while tPA-1 concentration in the plasma was decreased by dabigatran treatment 24 h after i.v. injection of cancer cells (Figure 4J). Here, SERPINE1 is linked to cancer.