In the study of the progress and treatment of RP, in addition to gene mutant mice models such as rd1 and rd10 (Chang et al., 2002), there are some convenient and rapid drug-induced RP models such as N-Methyl-N-nitrosourea (MNU) and sodium iodate (NaIO3) induced photoreceptor degeneration mice (Machalinska et al., 2010; Tao et al., 2015). The gene discussed is PDE6B; the disease is retinitis pigmentosa 1.