PDE6B and retinitis pigmentosa 1: The animal models of RP include gene mutant mice such as rd1, rd10 and cpfl1 (Gagliardi et al., 2019), pigs and mice with retinal photoreceptor degeneration caused by MNU (Chen et al., 2014; Choi et al., 2021) and retinal photoreceptor degeneration mice caused by light (Grimm and Reme, 2019).