Both log NT-proBNP and log hs-cTnT were inversely associated with GFR in a linear fashion in both CKD (β =  − 0.01, p < 0.001 and β =  − 0.01, p = 0.001) and CKD-T patients (β =  − 0.02, p = 0.004 and β =  − 0.007, p = 0.009). This evidence concerns the gene TNNT2 and chronic kidney disease.