F2 and gestational diabetes: Xiong et al [19] developed a prediction model for GDM risk in the first 19 weeks of gestation with several hepatic, renal, and coagulation function measures; they observed that a cutoff of prothrombin time and activated partial thromboplastin time could reliably predict GDM with a sensitivity of 88.3%, a specificity of 99.47%, and an AUROC of 94.2%.