PDCD1LG2 and posterior cortical atrophy: Zhao et al.24 reported that PD-L2 is a prognostic biomarker for PCa based on patients, and they also reported that the infiltration of T cells and macrophages is increased in the poor outcome group, which is also consistent with our work that M2 macrophages are linked with unfavorable prognosis, while the combination of immunocytes and clinical features could distinguish the different ends of recurrence25.