The(GT)n repeat polymorphisms in HO-1 have been associated with severeacute pancreatitis (49), encephalitis in HIVinfection (50), pediatric non-alcoholic fattyliver disease (51), and cancer (52), and lower levels of HO-1 are linked todiabetic retinopathy (53) and peripheralartery diseases (54). This evidence concerns the gene HMOX1 and retinal disorder.