When YBX1−/− AsPC-1 cells transfected with NLS-YBX1, NES-YBX1 or NLS-GSDME were inoculated into the pancreas of mice, the transfection of NES-YBX1 or NLS-GSDME barely rescued YBX1−/− tumour cells to allow tumour growth. This evidence concerns the gene YBX1 and neoplasm.