Using an optimized RIP-seq method, Merry et al. identified 148 lncRNAs interacting with DNMT1 in colon cancer cells [59], and the following investigation showed that one of these lncRNAs, DACOR1, could recruit DNMT1 and reprogram genome-wide DNA methylation [60]. The gene discussed is DNMT1; the disease is malignant colon neoplasm.