CLIP4 and neoplasm: Similarly, a study by Jensen et al., defined three tumor-specific DNA methylation markers, known as Chromosome 9 Open Reading Frame 50 (C9orf50), Potassium Voltage-Gated Channel Subfamily Q Member 5 (KCNQ5) and CAP-Gly Domain Containing Linker Protein Family Member 4 (CLIP4) in circulating cell-free DNA.