Specifically, there is a fourfold increase in lung cysts (χ2 = 4.14 p = 0.04), a twofold increase in renal angiomyolipomas (χ2 = 14.14 p < 0.001), and a fivefold increase in liver angiomyolipomas (χ2 = 6.96 p = 0.008) if the patient has a TSC2 mutation compared to TSC1 mutation. This evidence concerns the gene TSC2 and kidney angiomyolipoma.