To determine the mechanism of how NCAPG affects the Wnt/β-catenin signaling pathway in CRC cells, we measured protein expression levels of critical members of the Wnt/β-catenin signaling pathway, i.e. GSK3β, β-catenin, and p-β-catenin and their target genes, c-myc and cyclin D1. This evidence concerns the gene GSK3B and colorectal carcinoma.