ACD: Anemia of chronic disease, AI: Inflammation anemia, CHr: Reticulocyte hemoglobin content, CKD: Chronic kidney disease, CRF: Chronic renal failure ESRD: End-stage renal disease, ID: Iron deficiency, IDA: Iron deficiency anemia, MCV:Mean corpuscular volume, NIDA: Non-iron deficiency anemia, TM: β-Talasemia minor, TSAT: Transferrin Saturation. The gene discussed is TF; the disease is anemia (phenotype).