The elevated levels of IL-1β, IL-6, TNF-α, IL-18, and IL-37 in sepsis have previously been reported (Ge, Huang & Yao, 2019; Lendak et al., 2018; Mierzchala-Pasierb et al., 2019; Song et al., 2019; Wu et al., 2021). The gene discussed is IL18; the disease is Sepsis.