IL6 and Sepsis: In this context, some laboratory biomarkers, such as procalcitonin (PCT) (Vijayan et al., 2017), C reactive protein (CRP) (Hofer et al., 2012), interleukin-6 (IL-6) (Ma et al., 2016), serum amyloid A (SAA) (Arnon et al., 2007), and heparin-binding protein (HBP) (Yang et al., 2019), were widely applied in the diagnosis and predicting outcomes of sepsis in the clinical practice, but with the unsatisfied sensitivity and specificity.