ATXN3 and multiple system atrophy, cerebellar type: In contrast, only a very smallreduction was observed in DNsil in SCA3 patients (Row 6, Fig. 1 and Supplementary Fig. 4).Considering DNbulk, a significant reduction in dentate volume waspresent in SCA1, SCA2, FRDA and MSA-C patients, and to a lesser degree in SCA3patients (Row 7, Fig. 1 and Supplementary Figs3–5).