Regarding genotypes, the majority of the NC-CAH patients (Group I) were homozygous for the p.Val282Leu pathogenic variant (58% of the children and 50% of the adults) or compound heterozygous for the p.Val282Leu/del/conv promotor CYP21A2 pathogenic variants (17% of the children and 50% of the adults). The gene discussed is CYP21A2; the disease is congenital adrenal hyperplasia.