GSDMD and carcinoma of esophagus: Using TCGA data, we statistically compared the expression of GSDMD in cancer tissues and adjacent tissues, and found that, in a variety of tumours, including breast cancer, liver cancer, oesophageal cancer, and head and neck squamous-cell carcinoma, the expression of GSDMD in cancer tissues was significantly higher than that in adjacent tissues (Fig. 1A).