MKI67 and squamous cell carcinoma: In addition, male sex, age >60 years, III and IV pathological stage, pleural invasion, smoking status, necrosis, STAS, vascular invasion, positive PD-L1 expression, Ki67 ≥ 15%, lymphatic metastasis, morphology with solid and micropapillary components, squamous carcinoma and other pathological types were significantly associated with shorter OS and PFS.