MRC1 and neoplasm: However, our previous study shows no engulfment of CD206+ tumour‐associated macrophages by i.t. administration of UC CTL EVs (Seo et al., 2018), considering that tumour‐associated macrophages are in different stages of differentiation from conventional M2 macrophages and Kupffer cells, and do not participate in the elimination of MV‐like EVs as a nucleic acid cargo.