Expression of glucose transporter proteins GLUT‐1 and GLUT‐3 is reduced in the endothelium of microvessels in the cerebral cortex, and hippocampus in AD [233, 234, 235, 236, 237], and GLUT‐1 levels are reduced in circulating brain endothelial cells in mild AD [238]. The gene discussed is SLC2A3; the disease is Alzheimer disease.