TNF and neoplasm: High levels of both PPARs also separated responders from non-responders receiving TNFα-neutralizing mAbs, GSE16879, E-MTAB-7604 or Vedolizumab that block the α4β7 integrin to prevent selective gut inflammatory, GSE73661 (ROC AUC 0.63-0.89, Fig. 2d), inactive disease from active disease (two independent cohorts ROC AUC above 0.93; Fig. 2d), and quiescent UC that progressed, or not to neoplasia (ROC AUC = 1.00 for qUC vs. nUC; Fig. 2d).