A high level of PPARA and PPARG was also able to distinguish healthy from diseased samples in diverse murine models of colitis (Fig. 2e); but such separation was most effectively noted in some models (Citrobacter infection-induced colitis, adoptive T-cell transfer, TNBS, and IL10−/−), but not in others (DSS, and TNFR1/2−/−). Here, PPARA is linked to colitis.