Since we do not find expression of MIF-associated chemokine receptors on eosinophils, it appears possible that our results, and earlier work demonstrating abated eosinophilia in the absence of MIF27,28,65, reflects an indirect induction of eosinophils by another, MIF-responsive, CXCR4+ cell type, most likely the ILC2 subset. The gene discussed is CXCR4; the disease is Increased total eosinophil count.