BCL2 and polycystic ovary syndrome: As shown in Fig. 2A,B, the mRNA and protein expression levels of the pro-apoptosis gene Bax were upregulated in GCs exposed to PCOS-FF derived exosomes, while the mRNA and protein expression levels of the anti-apoptosis gene Bcl-2 were downregulated in GCs exposed to PCOS-FF derived exosomes.