CHKA and colorectal carcinoma: Seventeen KEGG enrichment pathways in SW620 cells were the same as predicted by the above network pharmacology, whereas only one such pathway in SW480 cells was identified, namely the “cell cycle” pathway, which was a common pathway of the three (network-predict pathway, SW480-RNA-Seq pathway and SW620-RNA-Seq pathway) (Fig. 4C) and also a key pathway for anti-CRC CKI.