In addition to various cancer-related pathways, the predicted pathways mainly included adherens junction, transcriptional misregulation in cancer, signaling pathways regulating pluripotency of stem cells, Wnt, focal adhesion, Happo, PI3K-Akt, central carbon metabolism in cancer, cell cycle, HIF1, ErbB, FoxO, CRC, microRNAs in cancer, proteoglycans in cancer, p53, and pathways in cancer (Supplementary Table S4). This evidence concerns the gene AKT1 and colorectal carcinoma.