TP53 and cancer: In addition to various cancer-related pathways, the predicted pathways mainly included adherens junction, transcriptional misregulation in cancer, signaling pathways regulating pluripotency of stem cells, Wnt, focal adhesion, Happo, PI3K-Akt, central carbon metabolism in cancer, cell cycle, HIF1, ErbB, FoxO, CRC, microRNAs in cancer, proteoglycans in cancer, p53, and pathways in cancer (Supplementary Table S4).