PRMT7 and chronic obstructive pulmonary disease: Inline, monocyte-like macrophages were greater in the BAL of COPD patients concomitant with increased expression of PRMT7. Although previously published data showed a crucial role of PRMT7 in regulating plasma cell differentiation through Bcl634, the here identified role of PRMT7 in regulating immune cell adhesion and transmigration is specific for monocytes, since neutrophil and B and T cell recruitment was not impaired in the absence of PRMT7 upon CS or elastase exposure.