PRMT6 and chronic obstructive pulmonary disease: PRMT6 was recently described to also regulate inflammation in an animal model of emphysema16, while PRMT6 expression increased in the lungs of COPD patients from one cohort (GSE76925) (Supplementary Fig. 1i, its expression did not significantly change in the two other cohorts (Supplementary Fig. 1h, j, k) or mice exposed to CS (Supplementary Fig. 1l).