Moreover, the levels of autophagy were markedly decreased in PC cells co-transfected with circATG7 lentivirus/miR-766-5p mimic, circATG7 lentivirus/HUR siRNA, and circATG7 lentivirus/3MA compared with cells transfected with circATG7 lentivirus (Fig. 7E, F). This evidence concerns the gene ELAVL1 and pachyonychia congenita.