GRIA1 and schizophrenia: We have argued previously that impaired short-term habituation may be a key pathological mechanism towards the aberrant assignment of salience in schizophrenia [7, 20, 25, 27, 51] and that GluA1 in CA2/CA3 is key in regulating spatial short-term habituation via functional connectivity in the theta frequency range (theta coherence) [33].