The potential clinical significance of the ATP11B-CMTM6 complex in pancreatic cancer evaluated by TCGA data sets revealed that ATP11B was significantly correlated with tumor stage and pathologic grade (online supplemental figure S10A, B), while CMTM6 was associated with the pathologic grade (online supplemental figure S10C, D). Here, CMTM6 is linked to familial pancreatic carcinoma.