METTL3 and head and neck squamous cell carcinoma: Simultaneously, univariate Cox regression analysis revealed that tumor grade, clinical stage, TNM stage, and METTL3 expression were substantially associated with the overall survival of HNSCC patients (Fig. 1H), and multivariate Cox regression analysis showed that only METTL3 expression was an independent prognostic factor for HNSCC patients (Fig. 1I).