Consistently, BIRC3 protein in induced sputum supernatant remarkably increased in asthma (p = 0.0001) (Fig. 4C), and the AUC of the ROC curve was 0.8906 (p < 0.0001) (Fig. 4D), which further demonstrate a good diagnostic capacity of BIRC3 in asthma. Here, BIRC3 is linked to asthma.