Validation of 6 biomarkers with the highest importance score in TCGA and CGGA cohorts revealed that HS3ST1, and CNN3 were overexpressed in astrocytoma, while SLAIN1, ABTB2, TRIM67 and DRG2 were overexpressed in oligodendroglioma (Fig. 6L, M). The gene discussed is CNN3; the disease is oligodendroglioma.