Lysine (K)-specific demethylase 4A (KDM4A/JMJD2A) is a member of the Jumonji domain 2 histone demethylases family [19] that catalyses histone demethylation from lysine residues, transcriptionally regulates gene expressions in tumor cells, and serves as a potential therapeutic target for cancers [20–22]. Here, KDM4A is linked to neoplasm.