After generation of iPSCs (Fig. S1, A) and MNs (Fig. S1, B) of healthy individuals and ALS patients carrying C9orf72, SOD1 and TARDBP mutations, we profiled the miRNA transcriptome of ALS-MNs by TaqMan® Low Density Arrays (TLDA). The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.