UCHL1 and brain injury: In this cohort of 349 patients with mild traumatic brain injury, the Canadian CT Head Rule (CCHR), the New Orleans Criteria (NOC), and GFAP plus UCH-L1 had 100% sensitivity for detecting lesions on CT, but the CCHR had the highest specificity (33%), followed by GFAP plus UCH-L1 (25%) and the NOC (16%).