This could explain why Rho kinase block reduces acute kidney injury (Kentrup et al., 2011; Prakash et al., 2008; Teraishi et al., 2004; Versteilen et al., 2011; Versteilen et al., 2006), as we have confirmed using kidney injury molecule-1 (Kim-1) as a marker (Figure 7c and d). This evidence concerns the gene HAVCR1 and urogenital neoplasm.