Additionally, measurement of the tumor volume after 31-day treatment, revealed that the mean tumor volume of the (DTXL + siRNA)@NPs-ALN group was 1.73 cm3, which was much smaller than those of the PBS group (21.33 cm3), free (DTXL + siRNA) group (16.17 cm3) and (DTXL + siRNA)@NPs group (9.30 cm3) (Figure 8(E)). The gene discussed is ARLN; the disease is neoplasm.