CFH and age-related macular degeneration: There were also no significant interaction effects between CFI type 1 RV and ARMS2 p.A69S heterozygous (OR 1.29, 95% CI 0.25 to 5.98; P = 0.74) or CFH p.Y402H heterozygous (OR 1.45, 95% CI 0.45 to 5.49; P = 0.55) states on AMD risk.