Type 1 and type 2 diabetes as well as uncontrolled hyperglycemia increase the risk for poor COVID-19 outcome (139, 140, 143, 148–150). The association between high HbA1c and increased mortality remains controversial (151–154). Especially for type 2 diabetes, use of insulin is linked to higher mortality (153, 155). The gene discussed is INS; the disease is COVID-19.