Angiotensin converting enzyme I (ACE) is an enzyme that plays a key role in blood pressure control by catalyzing the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor and a aldosterone production enhancer that increases sodium retention22,23, thus deviations on its regular function may be implicated in pathogenesis of high blood pressure. This evidence concerns the gene ACE and hypertensive disorder.